BR Shuman, M Goudriaan, L Bar-On, MH Schwartz, K Desloovere, KM Steele (2016) “Repeatability of muscle synergies within and between days for typically developing children and children with cerebral palsy.” Gait & Posture.

BR Shuman, M Goudriaan, L Bar-On, MH Schwartz, K Desloovere, KM Steele (2016) “Repeatability of muscle synergies within and between days for typically developing children and children with cerebral palsy.” Gait & Posture.

Journal article in Gait and Posture:

Filtering parameters impact the results from muscle synergy analyses.

Top: Average tVAF for day 1 and day 2 in TD and CP calculated from all measured gait cycles. The LME model identified a significant difference in synergy complexity between TD and CP for n = 1–5 synergies. Bottom: Average tVAF for each of the three walking speeds in TD and CP from both days. Walking speed had a significant effect on synergy complexity for tVAF of 1–5 synergiesAbstract: Muscle synergies are typically calculated from electromyographic (EMG) signals using nonnegative matrix factorization. Synergies identify weighted groups of muscles that are commonly activated together during a task, such as walking. Synergy analysis has become an emerging tool to evaluate neuromuscular control; however, the repeatability of synergies between trials and days has not been evaluated. The goal of this study was to evaluate the repeatability of synergy complexity and structure in unimpaired individuals and individuals with cerebral palsy (CP). EMG data were collected from eight lower-limb muscles during gait for six typically developing (TD) children and five children with CP on two separate days, over three walking speeds. To evaluate synergy complexity, we calculated the total variance accounted for by one synergy (tVAF1). On a given day, the average range in tVAF1 between gait cycles was 18.2% for TD and 19.1% for CP. The average standard deviation in tVAF1 between gait cycles was 4.9% for TD and 5.0% for CP. Average tVAF1 calculated across gait cycles was not significantly different between days for TD or CP participants. Comparing synergy structure, the average (standard deviation) within day correlation coefficients of synergy weights for two or more synergies were 0.89 (0.15) for TD and 0.88 (0.15) for CP. Between days, the average correlation coefficient of synergy weights for two or more synergies was greater than 0.89 for TD and 0.74 for CP. These results demonstrate that synergy complexity and structure averaged over multiple gait cycles are repeatable between days in both TD and CP groups.

Webinar: Synergy-based Control in OpenSim

QuantifyControlJoin us January 27th for an OpenSim webinar lead by our director, Kat Steele.

Details

Title: Synergy-based Control in OpenSim: Coupled Muscle Activity in Static Optimization
Speakers: Kat Steele, University of Washington
Time: Wednesday, January 27, 2016 at 10:00 a.m. Pacific Standard Time
Registration: To register for this event, click HERE. (webinar is free, but registration is required)

Abstract

How humans control movement remains an open question. One theory suggests that muscles may be activated in weighted groups, commonly referred to as muscle synergies, modes, or modules. A small number of synergies have been shown to describe
muscle activity in both animals and humans during tasks such as walking and reaching; however, whether these synergies reflect underlying neural control or other constraints remains unclear. An advantage of musculoskeletal simulation is that we can specify and test different control strategies.

In this webinar, Dr. Steele will discuss an OpenSim plug-in that lets users couple the activation of multiple muscles in weighted groups through static optimization. She will demonstrate applications of this plug-in for evaluating synergy-based control and testing the impacts of variable muscle weightings on tibiofemoral contact forces.

More information about this work can be found within the publication“Consequences of biomechanically constrained tasks in the design and interpretation of synergy analyses.”

Upcoming Webinars for Graduate Students and Academics

SWE

Join us for the following AccessEngineering Webinars! If you would like to attend one or more, please register for the respective topic by following the link provided. (Please note, all of the webinars are scheduled in Eastern Daylight Time)

 

Choosing and Delivering a High Quality Online Program
Friday, Dec 4th, 2015 11:00 am – 12:00 pm (EDT)

About the Webinar:
This webinar will focus on three aspects of distance education: (1) how Kettering University Online develops high quality online programs; (2) how can students choose a high quality online program to enroll; and (3) how can potential instructors find a high quality institution to teach. There will be presentations and Q&A sessions about each aspect.

Presenter: Dr. Christine Wallace

Register for this Webinar


 

AccessEngineering: Strategies to support individuals with disabilities pursuing careers in engineering – Part 1
Monday, December 7th, 2015 1:00 pm – 2:00 pm (EDT)

About the Webinar:
This webinar focuses on a new NSF initiative, AccessEngineering, which (1) supports and promotes individuals with disabilities in pursuing engineering, and (2) integrates universal design and accessibility topics into the engineering curriculum. In particular, this webinar will discuss topics including communication tips and how you can best support individuals with disabilities in engineering, and best practices for making makerspaces, labs and machine shops accessible.

Presenters: Sheryl Burgstahler, Richard Ladner, Maya Cakmak, Kat Steele, Brianna Blaser

Register for this Webinar

 


Patents: An Introduction for Inventors, Part One
Friday, December 11th, 2015 2:00 pm – 3:00 pm (EDT)

About the Webinar:
This presentation series is a basic introduction to patents and an overview of issues and practices to be considered by prospective patent inventors and patent owners. Part One focuses on providing a basic overview of patents and need-to-know information for inventors to streamline the patenting process. The basic overview explains what patents are, how patents relate to other forms of intellectual property, what requirements must be met for patenting an invention in the U.S., basic considerations for patenting an invention internationally, and how patents provide value to their owners. The overview of information for inventors covers inventorship and ownership issues, when to file for a patent, how to avoid sinking a patent application with one’s own publications, and various good practices for inventors to follow regarding disclosures and record-keeping.

Presenter: Michael Gamble

Register for this Webinar


 

AccessEngineering: Strategies to support individuals with disabilities pursuing careers in engineering – Part 2
Tuesday, January 19th, 2016 1:00 pm – 2:00 pm (EDT)

About the Webinar:
This webinar focuses on a new NSF initiative, AccessEngineering, which (1) supports and promotes individuals with disabilities in pursuing engineering, and (2) integrates universal design and accessibility topics into the engineering curriculum. In particular, this webinar will discuss topics including communication tips and how you can best support individuals with disabilities in engineering, and best practices for making makerspaces, labs and machine shops accessible. Part 2 of this webinar series will focus on strategies for easily integrating universal design and accessibility topics into engineering education.

Presenters: Sheryl Burgstahler, Richard Ladner, Maya Cakmak, Kat Steele

Register for this Webinar

SSM Lee, D Gaebler-Spira, LQ Zhang, WZ Rymer, KM Steele, (2016) “Use of shear wave ultrasound elastography to quantify muscle properties in cerebral palsy.” Clinical Biomechanics

Sample ultrasound images from gastrocnemius and tibialis anterior showing greater shear wave velocity on more affected limb.

Journal article in Clinical Biomechanics:

Kat Steele partnered with Sabrina Lee from Northwestern University and the Rehabilitation Institute of Chicago to investigate shearwave ultrasound elastography as a new tool to quantify changes in muscle properties in cerebral palsy.

Sample ultrasound images from gastrocnemius and tibialis anterior showing greater shear wave velocity on more affected limb.Abstract: Individuals with cerebral palsy tend to have altered muscle architecture and composition, but little is known about the muscle material properties, specifically stiffness. Shear wave ultrasound elastography allows shear wave speed, which is related to stiffness, to be measured in vivo in individual muscles. Our aim was to evaluate the material properties, specifically stiffness, as measured by shear wave speed of the medial gastrocnemius and tibialis anterior muscles in children with hemiplegic cerebral palsy across a range of ankle torques and positions, and fascicle strains. Shear wave speed was measured bilaterally in the medial gastrocnemius and tibialis anterior over a range of ankle positions and torques using shear wave ultrasound elastography in eight individuals with hemiplegic cerebral palsy. B-mode ultrasound was used to measure muscle thickness and fascicle strain. Shear waves traveled faster in the medial gastrocnemius and tibialis anterior of the more-affected limb by 14% (P = 0.024) and 20% (P = 0.03), respectively, when the ankle was at 90°. Shear wave speed in the medial gastrocnemius increased as the ankle moved from plantarflexion to dorsiflexion (less affected: r2 = 0.82, P < 0.001; more-affected: r2 = 0.69, P < 0.001) and as ankle torque increased (less affected: r2 = 0.56,P < 0.001; more-affected: r2 = 0.45, P < 0.001). In addition, shear wave speed was strongly correlated with fascicle strain (less affected: r2 = 0.63, P < 0.001; more-affected: r2 = 0.53, P < 0.001). The higher shear wave speed in the more-affected limb of individuals with cerebral palsy indicates greater muscle stiffness, and demonstrates the clinical potential of shear wave elastography as a non-invasive tool for investigating mechanisms of altered muscle properties and informing diagnosis and treatment.