Congratulations to Dr. Megan Ebers on earning her Doctorate in Mechanical Engineering! Dr. Eber’s PhD thesis dissertation was titled Machine Learning for Dynamical Models of Human Movement. Congratulations and best of luck as you move forward as a Postdoc in the AMATH department at UW!
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Introducing Dr. Elijah Kuska
Congratulations to Dr. Elijah Kuska on earning his Doctorate in Mechanical Engineering! Dr. Kuska’s PhD thesis dissertation was titled In Silico Techniques to Improve Understanding of Gait in Cerebral Palsy. Congratulations and best of luck as you move forward as an assistant teaching professor at the Colorado School of Mines!
AM Spomer, RZ Yan, MH Schwartz, KM Steele (2023) “Motor control complexity can be dynamically simplified during gait pattern exploration using motor control-based biofeedback”
Journal Article in Journal of Neurophysiology
Understanding how the central nervous system coordinates diverse motor outputs has been a topic of extensive investigation. Although it is generally accepted that a small set of synergies underlies many common activities, such as walking, whether synergies are equally robust across a broader array of gait patterns or can be flexibly modified remains unclear.
Aim: The aim of this study was to characterize the robustness of synergies to changing biomechanical constraints during walking. Specifically, we evaluated the extent to which nondisabled individuals could modulate both synergy structure and complexity while using motor control biofeedback to drive broad gait pattern exploration.
Methods: We evaluated the extent to which synergies changed as nondisabled adults (n = 14) explored gait patterns using custom biofeedback. Secondarily, we used Bayesian additive regression trees to identify factors that were associated with synergy modulation.
Results: Participants explored 41.1 ± 8.0 gait patterns using biofeedback, during which synergy recruitment changed depending on the type and magnitude of gait pattern modification. Specifically, a consistent set of synergies was recruited to accommodate small deviations from baseline, but additional synergies emerged for larger gait changes. Synergy complexity was similarly modulated; complexity decreased for 82.6% of the attempted gait patterns, but distal gait mechanics were strongly associated with these changes. In particular, greater ankle dorsiflexion moments and knee flexion through stance, as well as greater knee extension moments at initial contact, corresponded to a reduction in synergy complexity.
Interpretation: Taken together, these results suggest that the central nervous system preferentially adopts a low-dimensional, largely invariant control strategy but can modify that strategy to produce diverse gait patterns. Beyond improving understanding of how synergies are recruited during gait, study outcomes may also help identify parameters that can be targeted with interventions to alter synergies and improve motor control after neurological injury.
New & Noteworthy: We used a motor control-based biofeedback system and machine learning to characterize the extent to which nondisabled adults can modulate synergies during gait pattern exploration. Results revealed that a small library of synergies underlies an array of gait patterns but that recruitment from this library changes as a function of the imposed biomechanical constraints. Our findings enhance understanding of the neural control of gait and may inform biofeedback strategies to improve synergy recruitment after neurological injury.
NL Zaino, M Yamagami, DJ Gaebler-Spira, KM Steele, KF Bjornson, HA Feldner (2022) “‘That’s frustrating’: Perceptions of ankle foot orthosis provision, use, and needs among people with cerebral palsy and caregivers”
Journal Article in Prosthetics and Orthotics International:
This research provides insights into the lived experiences of individuals with CP and their caregivers regarding the process of obtaining and using an AFO. Further opportunities exist to support function and participation of people with CP by streamlining AFO provision processes, creating educational materials, and improving AFO design for comfort and ease of use.
Aim: The study objective was to evaluate the lived experiences of individuals with CP and their caregivers regarding AFO access, use, and priorities. We examined experiences around the perceived purpose of AFOs, provision process, current barriers to use, and ideas for future AFO design.
Method: Secondary data analysis was performed on semistructured focus groups that included 68 individuals with CP and 74 caregivers. Of the focus group participants, 66 mentioned AFOs (16 individuals with CP and 50 caregivers). De-identified transcripts were analyzed using inductive coding, and the codes were consolidated into themes.
Results: Four themes emerged: 1) AFO provision is a confusing and lengthy process, 2) participants want more information during AFO provision, 3) AFOs are uncomfortable and difficult to use, and 4) AFOs can benefit mobility and independence. Caregivers and individuals with CP recommended ideas such as 3D printing orthoses and education for caregivers on design choices to improve AFO design and provision.
Interpretation: Individuals with CP and their caregivers found the AFO provision process frustrating but highlight that AFOs support mobility and participation. Further opportunities exist to support function and participation of people with CP by streamlining AFO provision processes, creating educational materials, and improving AFO design for comfort and ease of use.
Introducing Dr. Alyssa Spomer!!
Congratulations to Dr. Alyssa Spomer on earning her Doctorate in Mechanical Engineering! Dr. Spomer’s PhD thesis dissertation was titled Evaluating multimodal biofeedback to target and improve motor control in cerebral palsy. Congratulations and best of luck as you move forward as a Clinical Scientist at Gillette Children’s. Best of luck in Minnesota!