Discrepancy modeling is a unique and innovative tool that complements current biomechanical modeling approaches and may accelerate the discovery of individual-specific mechanisms driving responses to exoskeletons, other assistive devices, and clinical interventions.
Aim:This study aims to leverage a neural network-based discrepancy modeling framework to quantify complex changes in gait in response to passive ankle exoskeletons in non-disabled adults. It hypothesized that (i) the Nominal model would predict Exo kinematics and EMG less accurately than for the Nominal condition, and (ii) the Augmented (Nominal+Discrepancy) model would capture greater variance in Exo kinematics and EMG than the Nominal model.
Method: This study analyzed gait data for 12 non-disabled adults during treadmill walking in bilateral passive ankle exoskeletons at a self-selected speed, results of which were used in participant-specific continuous-time neural network with discrepancy models to predict gait responses.
Results: Discrepancy modeling successfully quantified individuals’ exoskeleton responses without requiring knowledge about physiological structure or motor control. However, additional measurement modalities and/or improved resolution are needed to characterize Exo gait, as the discrepancy may not comprehensively capture response due to unexplained variance in Exo gait.
Interpretation: These techniques can be used to accelerate the discovery of individual-specific mechanisms driving exoskeleton responses, thus enabling personalized rehabilitation.
This work highlights the potential of data-driven models grounded in dynamical systems theory to predict complex individualized responses to ankle exoskeletons., without requiring explicit knowledge of the individual’s physiology or motor control
Aim: Evaluate the ability of three classes of subject-specific phase-varying (PV) models to predict kinematic and myoelectric responses to ankle exoskeletons during walking, without requiring prior knowledge of specific user characteristics.
Method: Data from 12 unimpaired adults walking with bilateral passive ankle exoskeletons were captured. PV, linear PV (LPV), and nonlinear PV (NPV) models leveraged Floquet theory to kinematics and muscle activity in response to three exoskeleton torque conditions.
Results: The LPV model’s predictions were more accurate than the PV model when predicting less than 12.5% of a stride in the future and explained 49–70% of the variance in hip, knee and ankle kinematic responses to torque. The LPV model also predicted kinematic responses with similar accuracy to the more-complex NPV model. Myoelectric responses were challenging to predict with all models, explaining at most 10% of the variance in responses.
Interpretation: This work highlights the potential of data-driven PV models to predict complex subject-specific responses to ankle exoskeletons and inform device design and control.
This retrospective analysis demonstrated that energy consumption is not reduced after rhizotomy when compared to matched controls with cerebral palsy.
Aim: To determine whether energy consumption changes after selective dorsal rhizotomy (SDR) among children with cerebral palsy (CP).
Method: We retrospectively evaluated net nondimensional energy consumption during walking among 101 children with bilateral spastic CP who underwent SDR (59 males, 42 females; median age [5th centile, 95th centile] 5y 8mo [4y 2mo, 9y 4mo]) compared to a control group of children with CP who did not undergo SDR. The control group was matched by baseline age, spasticity, and energy consumption (56 males, 45 females; median age [5th centile, 95th centile] 5y 8mo [4y 1mo, 9y 6mo]). Outcomes were compared at baseline and follow‐up (SDR: mean [SD] 1y 7mo [6mo], control: 1y 8mo [8mo]).
Results: The SDR group had significantly greater decreases in spasticity compared to matched controls (–42% SDR vs –20% control, p<0.001). While both groups had a modest reduction in energy consumption between visits (–12% SDR, –7% control), there was no difference in change in energy consumption (p=0.11) or walking speed (p=0.56) between groups.
Interpretation: The SDR group did not exhibit greater reductions in energy consumption compared to controls. The SDR group had significantly greater spasticity reduction, suggesting that spasticity had minimal impact on energy consumption during walking in CP. These results support prior findings that spasticity and energy consumption decrease with age in CP. Identifying matched control groups is critical for outcomes research involving children with CP to account for developmental changes.
Journal Article in Prosthetics & Orthotics International
Assessments of human movement are clinically important. However, accurate measurements are often unavailable due to the need for expensive equipment or intensive processing. For orthotists and therapists, shank-to-vertical angle (SVA) is one critical measure used to assess gait and guide prescriptions. Smartphone-based sensors may provide a widely-available platform to expand access to quantitative assessments.
Assess accuracy and repeatability of smartphone-based measurement of SVA compared to marker-based 3D motion analysis.
Four licensed clinicians (two physical therapists and two orthotists) measured SVA during gait with a smartphone attached to the anterior or lateral shank surface of unimpaired adults. We compared SVA calculated from the smartphone’s inertial measurement unit to marker-based measurements. Each clinician completed three sessions/day on two days with each participant to assess repeatability.
Average absolute differences in SVA measured with a smartphone versus marker-based 3D motion analysis during gait were 0.67 ± 0.25° and 4.89 ± 0.72°, with anterior or lateral smartphone positions, respectively. The inter- and intra-day repeatability of SVA were within 2° for both smartphone positions.
Smartphone sensors can be used to measure SVA with high accuracy and repeatability during unimpaired gait, providing a widely-available tool for quantitative gait assessments.
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The app for monitoring shank-to-vertical angle is available for you to download and use on either Android or iOS smartphone. Please complete THIS SURVEY which will then send you an e-mail with instructions for installation and use. This app is not an FDA approved medical device and should be used appropriately.