Cerebral Palsy

RESNA 2023 Conference: Mia Hoffman receives Student Scientific Paper Award

Katie Landwehr Awards, News, Presentation , , , ,

Nicole wearing a black dress and Mia wearing a floral dress standing in front of a large sign at the RESNA conference.Two lab members, Nicole Zaino and Mia Hoffman attended the annual Rehabilitation Engineering and Assistive Technology Society of North America (RESNA) Conference on July 24-26 in New Orleans, LA.

Big congratulations to Mia Hoffman for being selected as an awardee in the Student Scientific Paper Competition (SSPC).

Mia gave a podium presentation on “Exploring the World on Wheels: A Geospatial Comparison of Two Pediatric Mobility Devices”

Nicole was also selected to give an interactive poster presentation on “Quantifying Toddler Exploration in Seated and Standing Postures with Powered Mobility“. She also completed her time as the student board member for RESNA.

Way to go, Mia and Nicole!

BC Conner, AM Spomer, KM Steele, ZF Lerner (2022) “Factors influencing neuromuscular responses to gait training with a robotic ankle exoskeleton in cerebral palsy”

Yusuke Maruo JournalArticle, Publications , ,

Journal Article in Assistive Technology:

Our findings underscored the importance of monitoring how users change their gait kinematics when walking with the resistive device, with a specific emphasis on stance-phase lower limb extension. We also highlight the necessity of considering an individual’s functional status and amount of practice with the device, as well as more obvious factors, like device parameters. BART can be used early in the development of robotic gait training interventions to better understand complex and multifactorial user-device interactions.

Aim: Although ankle exoskeletons offer a promising means of augmenting gait training and enhancing independent mobility among individuals with neuromuscular disorders, response to existing paradigms is highly heterogeneous. In this study we aimed to identify factors which may affect how individuals with cerebral palsy (CP) interact with a resistive ankle exoskeleton during multi-day training to inform future device design and individualized tuning.

Method:We evaluated the gait mechanics (kinematics and muscle activity) of eight individuals with CP as they walked with bilateral ankle exoskeletons – designed to promote increased plantar flexor recruitment – during a seven-day training paradigm. These data along with pertinent device and participant parameters were input into a Bayesian Additive Regression Trees (BART) machine learning model to identify factors which were most associated with increased plantar flexor recruitment.

Results: Four themes emerged: 1) AFO provision is a confusing and lengthy process, 2) participants want more information during AFO provision, 3) AFOs are uncomfortable and difficult to use, and 4) AFOs can benefit mobility and independence. Caregivers and individuals with CP recommended ideas such as 3D printing orthoses and education for caregivers on design choices to improve AFO design and provision.

Interpretation: Individuals with CP and their caregivers found the AFO provision process frustrating but highlight that AFOs support mobility and participation. Further opportunities exist to support function and participation of people with CP by streamlining AFO provision processes, creating educational materials, and improving AFO design for comfort and ease of use.

NL Zaino, M Yamagami, DJ Gaebler-Spira, KM Steele, KF Bjornson, HA Feldner (2022) “‘That’s frustrating’: Perceptions of ankle foot orthosis provision, use, and needs among people with cerebral palsy and caregivers”

Yusuke Maruo JournalArticle, News, Publications , , ,

Journal Article in Prosthetics and Orthotics International:

This research provides insights into the lived experiences of individuals with CP and their caregivers regarding the process of obtaining and using an AFO. Further opportunities exist to support function and participation of people with CP by streamlining AFO provision processes, creating educational materials, and improving AFO design for comfort and ease of use.

Aim: The study objective was to evaluate the lived experiences of individuals with CP and their caregivers regarding AFO access, use, and priorities. We examined experiences around the perceived purpose of AFOs, provision process, current barriers to use, and ideas for future AFO design.

Method: Secondary data analysis was performed on semistructured focus groups that included 68 individuals with CP and 74 caregivers. Of the focus group participants, 66 mentioned AFOs (16 individuals with CP and 50 caregivers). De-identified transcripts were analyzed using inductive coding, and the codes were consolidated into themes.

Results: Four themes emerged: 1) AFO provision is a confusing and lengthy process, 2) participants want more information during AFO provision, 3) AFOs are uncomfortable and difficult to use, and 4) AFOs can benefit mobility and independence. Caregivers and individuals with CP recommended ideas such as 3D printing orthoses and education for caregivers on design choices to improve AFO design and provision.

Interpretation: Individuals with CP and their caregivers found the AFO provision process frustrating but highlight that AFOs support mobility and participation. Further opportunities exist to support function and participation of people with CP by streamlining AFO provision processes, creating educational materials, and improving AFO design for comfort and ease of use.

2020 Center for Translational Muscle Research

Dr. Steele MotorControl, Orthoses, Outreach, Presentation , , , , ,

How can we decipher human movement?

CTMR: White text on purple background, UW Center for Translational Muscle ResearchOur skeletal muscles have amazing structure. They provide elegant and efficient actuation to move and explore our worlds. But how do we understand how muscles produce movement?

Dr. Steele presents at the inaugural research symposium for the University of Washington Center for Translational Muscle Research. Her presentation shares examples for how we can use musculoskeletal simulation as a tool to connect muscle biology, dynamics, and mobility.

Slides | Transcript

NL Zaino, KM Steele, JM Donelan, MH Schwartz (2020) “Energy consumption does not change after selective dorsal rhizotomy in children with spastic cerebral palsy” Developmental Medicine & Child Neurology

Nicole JournalArticle, News, Publications , , , ,

Journal Article in Developmental Medicine & Child Neurology:

This retrospective analysis demonstrated that energy consumption is not reduced after rhizotomy when compared to matched controls with cerebral palsy.

Spasticity and net-nondimensionalized (NN) energy consumption for children with cerebral palsy (CP) who underwent a selective dorsal rhizotomy (SDR) and matched peers with CP who did not undergo SDR (control). (a) Baseline spasticity and NN energy consumption were similar between groups. Gray lines show normative values for typically developing (TD) peers from Gillette Children’s Specialty Healthcare. (b) Spasticity and NN energy consumption decreased significantly at follow-up for both groups. The SDR cohort had a significantly greater decrease in spasticity compared to the no-SDR group, but a similar decrease in NN energy consumption. Bars represent distributions for each group including outliers (*).

Aim: To determine whether energy consumption changes after selective dorsal rhizotomy (SDR) among children with cerebral palsy (CP).

Method: We retrospectively evaluated net nondimensional energy consumption during walking among 101 children with bilateral spastic CP who underwent SDR (59 males, 42 females; median age [5th centile, 95th centile] 5y 8mo [4y 2mo, 9y 4mo]) compared to a control group of children with CP who did not undergo SDR. The control group was matched by baseline age, spasticity, and energy consumption (56 males, 45 females; median age [5th centile, 95th centile] 5y 8mo [4y 1mo, 9y 6mo]). Outcomes were compared at baseline and follow‐up (SDR: mean [SD] 1y 7mo [6mo], control: 1y 8mo [8mo]).

Results: The SDR group had significantly greater decreases in spasticity compared to matched controls (–42% SDR vs –20% control, p<0.001). While both groups had a modest reduction in energy consumption between visits (–12% SDR, –7% control), there was no difference in change in energy consumption (p=0.11) or walking speed (p=0.56) between groups.

Interpretation: The SDR group did not exhibit greater reductions in energy consumption compared to controls. The SDR group had significantly greater spasticity reduction, suggesting that spasticity had minimal impact on energy consumption during walking in CP. These results support prior findings that spasticity and energy consumption decrease with age in CP. Identifying matched control groups is critical for outcomes research involving children with CP to account for developmental changes.